Autopsy

ALN-VSP02 is Alnylam's most advanced systemic RNAi system, and employs an initial generation LNP produced by Tekmira Pharmaceuticals Company. ALN-VSP comprises two siRNAs designed to target two genes critical for the ...

'Our findings might encourage physicians to consider that at least a few of their obese individuals might be suffering from a problem that can not be solved by eating much less and exercising more often,' Oliver said....

They found that pharmacological BACE1 inhibition decreased dendritic spine dynamics, decreased neurotransmission, and impaired cognition. Importantly, however, these disruptive results were dose dependent. Dr. Herms d...