Arthur Reingold

Michael C. Thigpen, M.D ., Cynthia G. Whitney, M.D., M.P.H., Nancy E. Messonnier, M.D., Elizabeth R. Zell, M.Stat., Ruth Lynfield, M.D., James L. Hadler, M.D., M.P.H., Lee H. Harrison, M.D., Monica M. Farley, M.D., Arthur Reingold, M.D., Nancy M. Bennett, M.D., Allen S. Craig, M.D., William Schaffner, M.D., Ann Thomas, M.D., Melissa M. Lewis, M.P.H., Elaine Scallan, Ph.D., and Anne Schuchat, M.D.1-4 Between 1986 and 1995, the incidence of bacterial meningitis from these five pathogens declined by 55 percent, owing to the usage of the H largely. Influenzae type b conjugate vaccine for infants, that was introduced in the United States in 1990.5 Since that time, additional interventions to prevent invasive disease from these pathogens have already been introduced6-8 .

The Collaborative Cross, begun in 2005 with a grant from the Ellison Medical Foundation, represents a fundamentally new method of conducting genetics aims and research to create 1, 000 strains of mice that feature the genetic diversity of the global world population. When finished in about five years, the research community will have access to an extremely versatile useful resource plus data that is the click of a mouse away. There will be other benefits aswell. With this approach, using a reference population which allows for high genetic diversity and large sample size, researchers can better examine combinations of genes responsible for diseases.